Fish-based gel caps
Convenient flip-open top
250mg* Rhodiola per softgel
115mg* omega-3s per softgel
Lab-certified pure and potent
No artificial preservatives or colors
No dairy, starch, wheat, yeast, sugar, or soy
Extracted from Rhodiola rosea root grown in Russia
Product of USA
*500mg Rhodiola + 230mg omega-3s per two-capsule serving
From Scandinavia to Siberia, northern and Asian peoples have long relied on this ancient medicinal root to enhance endurance and maintain healthy mood.
Modern researchers classify Rhodiola (rode-ee-oh-lah) as an "adaptogen" … meaning an agent that moderates the effects of physical and mental stress.
Rhodiola – also known as golden root, rose root, Aaron's rod, or Arctic root – has been the subject of substantial lab and clinical study, with most human trials affirming its reputed adaptogenic benefits.
Our Rhodiola extract is standardized to provide two key constituents in the amounts and proportions used in successful clinical studies: 3% rosavins and 1% salidroside.
Folk history and modern research
As early as 77 AD, the famed Greek physician Dioscorides recommended Rhodiola for enhanced strength and endurance.
Viking and Siberian peoples used it for endurance, and to support health and fertility.
Throughout Europe, Rhodiola rosea root appears in herbal tonics designed to reinforce resistance to cold, stress, and fatigue.
(Rhodiola rosea root tastes and smells of roses ... traits that account for the second part of the plant's Latin name.)
Extensive Soviet research prompted Western scientists to probe the plant for potential health benefits ... especially to support healthy mood.*
Among other effects, Rhodiola extract appears to enhance the transport of serotonin's precursors into the brain, inhibit disintegration of two key mood-regulating neurotransmitters (serotonin and dopamine), and prevent declines in neurotransmitter levels caused by excessive release of stress hormones.*
And Rhodiola rosea root is rich in polyphenols believed to exert beneficial effects on gene switches affecting stress- and aging-related degenerative processes, including oxidation and inflammation.*
Rhodiola cautions and drug interactions
- Rhodiola inhibits the CYP3A4 enzyme (which metabolizes many drugs, and is key to synthesis of cholesterol and steroidal hormones) and can affect the intracellular concentration of drugs metabolized by this enzyme. This is also true of grapefruit and pomegranate juices, which are more powerful inhibitors of this enzyme.
- Rhodiola inhibits P-gp activity and can interfere with the metabolism of certain drugs.
- Rhodiola inhibits the monoamine oxidase (MAO) A and B enzymes, which accounts in part for its mood benefits. It may therefore amplify the serotonergic effects of SSRI drugs such as Prozac, and raise or lower blood pressure. though that hypothesis is based on a cell study and therefore speculative.
- There is one reported case of significant tachyarrhythmia following ingestion of Rhodiola along with an antidepressant.
*These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.
- Abidov M, Crendal F, Grachev S, Seifulla R, Ziegenfuss T. Effect of extracts from Rhodiola rosea and Rhodiola crenulata (Crassulaceae) roots on ATP content in mitochondria of skeletal muscles. Bull Exp Biol Med. 2003 Dec;136(6):585-7.
- Brown RP, Gerbarg PL, Ramazanov Z. Rhodiola rosea: a phytomedicinal overview. Herbalgram. 2002;56:40-52. Accessed at http://cms.herbalgram.org/herbalgram/issue56/article2333.html
- De Bock K, Eijnde BO, Ramaekers M, Hespel P. Acute Rhodiola rosea intake can improve endurance exercise performance. Int J Sport Nutr Exerc Metab. 2004 Jun;14(3):298-307.
- Earnest CP, Morss GM, Wyatt F, Jordan AN, Colson S, Church TS, Fitzgerald Y, Autrey L, Jurca R, Lucia A. Effects of a commercial herbal-based formula on exercise performance in cyclists. Med Sci Sports Exerc. 2004 Mar;36(3):504-9.
- Huang SC, Lee FT, Kuo TY, Yang JH, Chien CT. Attenuation of long-term Rhodiola rosea supplementation on exhaustive swimming-evoked oxidative stress in the rat. Chin J Physiol. 2009 Oct 31;52(5):316-24.
- Memorial Sloan-Kettering Cancer Center - Rhodiola Monograph. Accessed at http://www.mskcc.org/cancer-care/herb/rhodiola.
- NYU Langone Medical Center. Rhodiola rosea. Accessed at http://www.med.nyu.edu/content?ChunkIID=111798
- Olsson EM, von Sch?ele B, Panossian AG. A randomised, double-blind, placebo-controlled, parallel-group study of the standardised extract shr-5 of the roots of Rhodiola rosea in the treatment of subjects with stress-related fatigue. Planta Med. 2009 Feb;75(2):105-12. Epub 2008 Nov 18.
- Skarpanska-Stejnborn A, Pilaczynska-Szczesniak L, Basta P, Deskur-Smielecka E. The influence of supplementation with Rhodiola rosea L. extract on selected redox parameters in professional rowers. Int J Sport Nutr Exerc Metab. 2009 Apr;19(2):186-99.
- Walker TB, Altobelli SA, Caprihan A, Robergs RA. Failure of Rhodiola rosea to alter skeletal muscle phosphate kinetics in trained men. Metabolism. 2007 Aug;56(8):1111-7.
- Walker TB, Robergs RA. Does Rhodiola rosea possess ergogenic properties? Int J Sport Nutr Exerc Metab. 2006 Jun;16(3):305-15. Review.