Review: So, I ordered this thinking "long term" about the potential use of an anti-inflammatory for the brain. No anecdotal evidence about THAT aspect... I have a joint which took a few nasty injuries 20 years ago (and probably is arthritic as a result) - and from time to time wakes me up to remind me of those injuries. In the past a strong NSAID was helpful. I might have taken it a few times a year. I haven't taken it in a while. It just dawned on me the other day that since I have been taking this regularly, I haven't had occasion to wonder where I stashed the prescription. The joint hasn't been terribly troublesome and it hasn't awakened me in the middle of the night. This is purely anecdotal - your results may vary. I wanted to share this in case it is useful to someone in a situation like mine. Not cheap, and be sure to read the details about drug interactions on the "details" tab. No idea if it's doing what I hoped it would when I made the purchase, but also joyfully aware that it sure DID help (me at least) with a bum knee.